Sophie Kerneis-Golsteyn , PhD
Professional Experience
I have taught Microbiology labs in France for three years to students in pharmaceutical school. I taught Microbiology seminars to master students. In Canada I have taught at the University of Lethbridge a Biology course for the FNTP program as well as a microbiology course HLSC2400. I have been teaching at the College since 2009 a Microbiology course and lab BIO1162, anatomy labs BIO1160, Human nutrition course BIO1155, Cell Biology course BIO1150.
I have worked in the Biotech ManRos for a year.
I have been working as a research scientist since 1994 first as a Post doc at ISREC in Switzerland for two years, then at the Pasteur Institute in Paris France as a post Doc for 2 years and then as a tenure research scientist for 9 years. Moving to Canada I worked at the Research Center of Lethbridge and at the University of Lethbridge as a research scientist. In 2016 I set up the Microbial Research Laboratory at Lethbridge College, I trained 23 students from various institutions. I obtained grants from NSERC, CARI and my master students obtained a Mc Cain scholarship to complete their master thesis in my laboratory.
Education
1991-1993 Ph.D. in Microbial Ecology; pathogenesis of microorganisms and anti-infectious agents, University Paris XI, Paris, France. Laboratory, Dr. A. Servin.
1991-1993 Formation in teaching 60 hours per year, University Paris XI, France.
1989-1990 Post-Graduate Diploma "(DEA)" in Microbial Ecology; pathogenesis of microorganisms and anti-infectious agents. University Paris XI, France. Laboratory, Dr. A. Zweibaum,
1989 Master of Science "Maîtrise" in Cell Biology - Genetics. University Paris VI, France.
1988 Bachelor of Science "Licence" Cell Biology and Animal Physiology. University Paris VI, France.
1986-1987 "D.E.U.G." Biophysics, University Paris VI, France.
-Molina, L., Allard, HK., Kernéis, SM., and RM Golsteyn. 2022. Connecting plant species and natural products from the Canadian prairie ecological zone to biomedical knowledge. Botany 100 (2), 231-245
-Tuescher, J.M., Tailfeathers, D., Kernéis, S.M., Baratte, B., Ruchaud, S., Bach, S., Batut, M., Pouny, I., Sautel, F., and R.M. Golsteyn. 2020. The Canadian Prairie Plant Thermopsis rhombifolia Contains Luteolin, a Flavone that Inhibits Cyclin Dependent Kinase 9 and Arrest Cells in the G1-Phase of the Cell Cycle. Journal of Natural Health Product Research. 2:1-14.
-Bosco, A., S. Kernéis, C. Tantapakul, W. Maneerat, B. Yeremy, D.E. Williams, R.J. Andersen and R. M. Golsteyn. 2021. Pulchelloid A, a sesquiterpene lactone chemical isolated from the Canadian prairie plant, Gaillardia aristata, inhibits mitosis in human cells. Molecular Biology Reports 48 (7), 5459-5471 2
-Kernéis, S., L.H. Swift, C.W. Lewis, C. Bruyère, N. Oumata, P. Colas, S. Ruchaud, J. Bain and R.M. Golsteyn. 2015. Natural product extracts of the Canadian prairie plant, Thermopsis rhombifolia, have anti-cancer activity in phenotypic cell based assays. Natural Product Research. 29:1026-1034.
-Kubara PM, Kernéis S, Studény A, Lanser BB, Meijer L, Golsteyn RM. 2012. Human cells enter mitosis with damaged DNA after treatment with pharmacological concentrations of genotoxic agents. Biochemical Journal. 446:373-381.
-Kernéis S., E. Caliot, H. Stubbe, A. Bogdanova, , J.P. Kraehenbuhl and E. Pringault. 2000. Molecular studies of the intestinal mucosal barrier physiopathology using cocultures of epithelial and immune cells: a technical update. Microbes and infection, 2:1119-1124.
-Kernéis S., and E. Pringault. 1999. Plasticity of the gastrointestinal epithelium, M cell paradigm and opportunism of pathogenic microorganisms. Seminars in Immunology, 11:205-215.
-Kernéis S. and E. Pringault. 1998. Immunological influences on intestinal proliferation and differentiation. Current Opinion in Gastroenterology, 14:504-509.
-Kernéis, S., Bogdanova, A., Kraehenbuhl, J.P., and E. Pringault. 1997. Conversion by Peyer’s patch lymphocytes of human enterocytes into M cells that transport bacteria. Science, 277:949-952.
-Kernéis, S. Phytobiotics to control infectious diseases in poultry. SPARK 2.0 Poultry Innovation Partnership. Red Deer, Alberta, October 17, 2022.
-Kernéis, S. Canadian phytobiotics to serve the health and agriculture industries: A solution to fight antibiotic resistance. Okanagan College’s sixth Annual RIPE. Online. May 2022
-Hand, N., Grisnich, K., Gerber, T., DuMontier L., Golsteyn R. and S. Kernéis. Phytobiotics to serve the poultry industry. Canadian Poultry Research Forum. Online. June 21-23, 2021.
-Kernéis, S. Antibiotics, antibiotic resistance, and the importance of finding new antibiotics. STEM fellowship, University of British Columbia, Online. January 21, 2021.
-Kernéis, S. Des antibiotiques dans les plantes en Alberta? Interview Radio Canada. 17 July 2020 -Kernéis, S. How plants can be the source of new antibiotics. Regina, Native Plant Society of Saskatchewan January 25, 2020. Plenary lecture.
-Puchbauer, M., Halmrast, A., Beck, C., Sanders, S., James, C., Ayley, C., Prozniak, M., Tailfeathers, D., MacRae, S., Golsteyn, R., Williams, D., Andersen, R., DuMontier, L. and S. Kernéis. The antibiotic properties of Alberta Prairie Plants. Natural Products in Drug Discovery and Health. Lisbon, Portugal, 28-31 July 2019.
-Puchbauer, M., Halmrast, A., Beck, C., James, C., Ayley, C., Prozniak, M., Tailfeathers, D., MacRae, S., Golsteyn, R., DuMontier, L, Williams, D., Andersen, R and S. Kernéis. Alberta Prairie plants- A new source of antibiotics. Natural Product Health Research Congress, Edmonton AB, 26-29 May 2019.
-Puchbauer, M., Halmrast, A., Beck, C., Sanders, S., James, C., Ayley, C., Prozniak, M., Tailfeathers, D., MacRae, S., Golsteyn, R., Williams, D., Andersen, R., DuMontier, L. and S. Kernéis.Why Alberta Prairie plants can be a source of new antibiotics? Research Symposium Lethbridge College. 14 May 2019.
-Kernéis, S. Bridge City News interview. Lethbridge. December 2018